Profusa (PFSA) Stock Jumps 96% After Third Reverse Split of 2026

TLDR

• Profusa stock surged 95.6% in pre-market trading on August 18, driven by its third reverse stock split of 2026
• The 1-for-4 reverse split took effect August 17, cutting shares outstanding from 2.42 million to roughly 605,726
• The ultra-thin float means even small buying pressure creates outsized price moves
• Profusa has a pending option to acquire G3 Vision Labs and a letter of intent for the PanOmics diagnostics platform
• The broader market was down on the day, with the Nasdaq off 1.3%, making this a purely stock-specific event

Profusa stock closed Monday at $4.53, up 27%, before jumping another 77% in after-hours to $8.02. By pre-market Tuesday, the stock had surged 95.6%, bringing the total move to near double its Monday close.

Profusa, Inc. Common Stock, PFSA

The driver is mechanical as much as anything else. Profusa executed a 1-for-4 reverse stock split effective 12:01 a.m. ET on August 17, its third reverse split of 2026. It followed a 1-for-25 split completed on July 7.

The split reduced shares outstanding from 2,422,906 to approximately 605,726. A new CUSIP number was assigned, and Tuesday’s pre-market was the first session with traders fully pricing in the new structure.

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